![]() ![]() Some patients continued to have symptoms during the six months of follow-up, Al-Aly says, and the severity of a patient’s disease typically worsened with each new COVID episode. Among them, roughly 10 percent had been infected with SARS-CoV-2 between two and four times. ![]() Department of Veterans Affairs (VA) between March 2020 and April 2022. Al-Aly’s team reviewed data from nearly half a million COVID patients treated by the U.S. Louis, and his colleagues concluded that reinfected people are twice as likely to die and three times as likely to be hospitalized with COVID than those infected only once, regardless of their vaccination status. A team of researchers led by Ziyad Al-Aly, a clinical epidemiologist at Washington University, in St. ![]() The first study of health risks from repeat infections was published last November. Evaluating the impacts of reinfection-especially with new viral variants arising that are successively more contagious-is an urgent priority, Fessel and other experts say. As more people get reinfected, they may be wondering: Do repeat infections lead to more severe COVID symptoms?Įvidence is still limited, but the available data show that while most reinfected people recover within a few days, “others are having a much rougher time,” says Josh Fessel, a pulmonologist at the National Center for Advancing Translational Sciences, in Bethesda, Md. Reinfections with SARS-CoV-2, the virus that causes the disease, are on the rise, dashing hopes that vaccination or prior disease confers long-lasting immunity to infection. ![]()
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